In PowerBuilder 12, PowerScript is a fully CLS-compliant .NET language and comes with the ability to deploy fully managed code. The older PowerBuilder IDE continues to be made available for vanilla PowerBuilder development. PowerScript is used primarily for building business applications. PowerBuilder applications are used by many companies in the financial sector. It is also used by government agencies worldwide, telcos, manufacturing, and healthcare companies. PowerBuilder database is in use at thousands of organizations around the world.
EzineMark article, by Daniel Wills